From being a masterpiece of the Renaissance to becoming a global obsession, here is how Leonardo da Vinci’s most famous — and world's most expensive — painting became pop culture’s most enduring artwork
French President Emmanuel Macron recently announced that Leonardo da Vinci’s Mona Lisa would receive a dedicated space as part of the Louvre’s decade-long “New Renaissance” renovation. The decision, one can argue, springs from the fact that the painting enjoys a distinctively unique position as an artistic treasure. It’s a singular work of art that has become an entire industry of sorts. When it was assessed at $100 million in 1962, it was already considered the most valuable painting in the world. If you take inflation into account, that figure would roughly be around $1.1 billion today. Or perhaps more.
Unlike other record-breaking sales of works by Vincent van Gogh or Pablo Picasso, the Mona Lisa — described as “the best known, the most visited, the most written about, the most sung about, [and] the most parodied work of art in the world” — is effectively priceless. It is so deeply connected with the Louvre and France’s cultural identity that no sale could ever be entertained. Its astronomical valuation, then, is not just about da Vinci’s genius, but about the market of meaning that has been built around it. Every book, every parody, every reinterpretation — from Andy Warhol’s screen prints to Dan Brown’s The Da Vinci Code — adds to its mythology, reinforcing the idea that this one image is not just art, but something closer to modern religion. Or at least some cult.
But what exactly is it that makes Mona Lisa — a rather unassuming, half-length portrait of a Florentine woman — worthy of such special treatment? And why, in an era when art is increasingly digitised or digitally stored on a blockchain (NFT, anyone?), does her enigmatique gaze and smiling eyes still command pilgrimage-level devotion? Well, the simple answer could be that Mona Lisa (oil on a white poplar panel) exists not just in the Louvre but in millions of reproductions, in advertisements, in political satire, in the very DNA of popular culture. With a dedicated space, it will continue its reign and its true power — its afterlife — will only expand.
A treasure lost and found
The answer also lies in how the painting has been historically manipulated, mythologised, and marketed into ubiquity. The Mona Lisa spawned memes before memes existed, a prototype for modern celebrity, and the ultimate symbol of mass obsession. The Louvre’s upcoming renovation acknowledges what the world already knows — the portrait of Lisa del Giocondo, the wife of Francesco del Giocondo, a wealthy silk merchant from Florence — is, in a way, bigger than the museum itself.
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For centuries after da Vinci painted the Mona Lisa in the early 1500s, she was respected but not yet worshipped. Kept in the French royal collection after King François I acquired it in 1518, the lady in the painting (did not command global fascination until the early 20th century. That moment arrived in 1911 when an Italian handyman named Vincenzo Peruggia, who had briefly worked at the museum as a glazier, stole the painting on August 21, 1911, believing he was restoring it to its homeland. The theft became an international scandal, setting off a media frenzy. For two years, the Mona Lisa was the world’s most wanted woman, her disappearance catapulted her to unprecedented fame.
When she was finally recovered in 1913, her mystique had become something else. Crowds swarmed the Louvre to see her — not just for her artistic merit (that’s another debate) but because she had become a legend. The painting had experienced an accidental branding moment: perhaps nothing fuels public fascination like an object that has been both lost and found.
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The 20th century further amped up her legend. In the 1950s and ’60s, the Mona Lisa embarked on a diplomatic world tour, meeting then US First Lady Jackie Kennedy in Washington (1962) and dazzling Tokyo’s elite at the national museum during the 50-day exhibition. By then, Mona Lisa was akin to an envoy, a cultural ambassador in oil paint. The painting’s stature only grew as modern media transformed her from an object of admiration to an object of obsession.
The ultimate meme
In the second half of the 20th century, popular culture lapped up the Mona Lisa in ways no other artwork had experienced. From Warhol’s pop-art reinterpretations to Marcel Duchamp’s irreverent L.H.O.O.Q — a cheap postcard reproduction, with a moustache and goatee — the painting was subsequently reimagined in sunglasses, turned into a Simpsons character, and adorned countless T-shirts, mugs, and phone cases. Unlike Michelangelo’s David or Botticelli’s Birth of Venus, the Mona Lisa can be toyed with, parodied, and even mocked without losing her lustre.

Mona Lisa, Andy Warhol, 1963
Its transformation into an object of kitsch was sealed in 1963 when Warhol mass-produced the painting. Suddenly, the Mona Lisa became a consumer product. The process continued in the digital age, when her face has been distorted, deep-faked, and AI-altered into infinite variations. The internet, it seems, has multiplied her power.
The Louvre’s decision to carve out a dedicated space for Mona Lisa, therefore, can be seen as a pragmatic response to the painting’s overwhelming popularity and worth. The museum, originally built to be a fortress and later a royal palace, was never designed to accommodate the millions who queue for a glimpse of her every year. Visitors jostle for position, experiencing the work through smartphones and selfie sticks, and the real painting continues to compete with its countless digital clones.
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Mona Lisa is, in a way, the museum’s greatest asset and biggest logistical headache. The decision to give it her own space is also a strategic move. The Louvre, like all major museums, faces pressure to modernise and remain relevant in an era when younger audiences engage with art, if at all, on social media. A dedicated Mona Lisa experience will likely include digital enhancements, interactive displays, and a controlled environment that optimises visitor engagement.
What the future holds
France has long used its cultural treasures as a form of soft power, and no artefact carries more weight than da Vinci’s masterpiece. Mona Lisa represents the country’s artistic supremacy, even though it was painted by an Italian. Its placement in the Louvre is a matter of national pride. Macron’s announcement comes at a time when France, like much of Europe, is in the throes of debates over national heritage and identity. The Louvre renovation, with Mona Lisa at its centre, is a statement about France’s place in the cultural hierarchy. It sends a clear message: France continues to be a centre of great art. Continues because it has always been a big draw; all our greats, including the likes of S.H. Raza, Amrita Sher-Gil Jehangir Sabavala and Ram Kumar, either studied in France or made it their home
So, what does the future hold for the world’s most famous face? With advancements in AI, virtual reality, and digital reproduction, we are approaching an era when people might interact with Mona Lisa in ways Leonardo could never have imagined. We may soon see immersive experiences where viewers can “step into” the painting, move around her imagined landscape, or even interact with an AI-generated version of her.
However, no matter how sophisticated technology becomes, the original painting will always be the ultimate destination. There is something irreplaceable about standing before the real thing, in the same room where Napoleon once had it hung in his bedroom. (It’s a different thing that when you actually see it in person, you may not find anything remotely remarkable about it as those who have been to the Louvre assert). That moment of connection — between the viewer and the 500-year-old brushstrokes of da Vinci — is something that cannot be downloaded or replicated. The Louvre’s decision to enshrine her in her own space is merely an acknowledgment of the obvious: she is not just part of art history — she is art history. And for as long as people continue to seek meaning in her half-smile, she will remain exactly where she has always been — at the centre of the world’s imagination.